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Mitochondrial Transport from Mesenchymal Stromal Cells to Chondrocytes Increases DNA Content and Proteoglycan Deposition In Vitro in 3D Cultures

OBJECTIVE: Allogeneic mesenchymal stromal cells (MSCs) are used in the 1-stage treatment of articular cartilage defects. The aim of this study is to investigate whether transport of mitochondria exists between chondrocytes and MSCs and to investigate whether the transfer of mitochondria to chondrocy...

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Detalles Bibliográficos
Autores principales: Korpershoek, Jasmijn V., Rikkers, Margot, Wallis, Fleur S. A., Dijkstra, Koen, te Raa, Marije, de Knijff, Peter, Saris, Daniel B. F., Vonk, Lucienne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924973/
https://www.ncbi.nlm.nih.gov/pubmed/36262105
http://dx.doi.org/10.1177/19476035221126346