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Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways
AIMS: Accumulating data demonstrates that new adult cardiomyocytes (CMs) are generated throughout life from pre-existing CMs, although the absolute magnitude of CM self-renewal is very low. Modifying epigenetic histone modifications or activating the Hippo-Yap pathway have been shown to promote adul...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925018/ https://www.ncbi.nlm.nih.gov/pubmed/36780463 http://dx.doi.org/10.1371/journal.pone.0281610 |