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Activation-pathway transitions in human voltage-gated proton channels revealed by a non-canonical fluorescent amino acid

Voltage-dependent gating of the voltage-gated proton channels (H(V)1) remains poorly understood, partly because of the difficulty of obtaining direct measurements of voltage sensor movement in the form of gating currents. To circumvent this problem, we have implemented patch-clamp fluorometry in com...

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Detalles Bibliográficos
Autores principales: Suárez-Delgado, Esteban, Orozco-Contreras, Maru, Rangel-Yescas, Gisela E, Islas, Leon D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925047/
https://www.ncbi.nlm.nih.gov/pubmed/36695566
http://dx.doi.org/10.7554/eLife.85836