State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels

The force-from-lipids hypothesis of cellular mechanosensation posits that membrane channels open and close in response to changes in the physical state of the lipid bilayer, induced for example by lateral tension. Here, we investigate the molecular basis for this transduction mechanism by studying t...

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Detalles Bibliográficos
Autores principales: Park, Yein Christina, Reddy, Bharat, Bavi, Navid, Perozo, Eduardo, Faraldo-Gómez, José D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925053/
https://www.ncbi.nlm.nih.gov/pubmed/36715097
http://dx.doi.org/10.7554/eLife.81445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925053/
https://www.ncbi.nlm.nih.gov/pubmed/36715097
http://dx.doi.org/10.7554/eLife.81445

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