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State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels
The force-from-lipids hypothesis of cellular mechanosensation posits that membrane channels open and close in response to changes in the physical state of the lipid bilayer, induced for example by lateral tension. Here, we investigate the molecular basis for this transduction mechanism by studying t...
Autores principales: | Park, Yein Christina, Reddy, Bharat, Bavi, Navid, Perozo, Eduardo, Faraldo-Gómez, José D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925053/ https://www.ncbi.nlm.nih.gov/pubmed/36715097 http://dx.doi.org/10.7554/eLife.81445 |
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