Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose co-transporter inhibitors

A long-term high-fat diet (HFD) causes obesity and changes in renal lipid metabolism and lysosomal dysfunction in mice, causing renal damage. Sodium-glucose co-transporter inhibitors, including phlorizin, exert nephroprotective effects in patients with chronic kidney disease, but the underlying mech...

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Detalles Bibliográficos
Autores principales: Saitoh, Sei, Takaki, Takashi, Nakajima, Kazuki, Wo, Bao, Terashima, Hiroshi, Shimo, Satoshi, Nguyen, Huy Bang, Thai, Truc Quynh, Kumamoto, Kanako, Kunisawa, Kazuo, Nagao, Shizuko, Tojo, Akihiro, Ohno, Nobuhiko, Takahashi, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925073/
https://www.ncbi.nlm.nih.gov/pubmed/36780539
http://dx.doi.org/10.1371/journal.pone.0281770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925073/
https://www.ncbi.nlm.nih.gov/pubmed/36780539
http://dx.doi.org/10.1371/journal.pone.0281770

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