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Control of sodium and potassium homeostasis by renal distal convoluted tubules

Distal convoluted tubules (DCT), which contain the Na-Cl cotransporter (NCC) inhibited by thiazide diuretics, undergo complex modulation to preserve Na(+) and K(+) homeostasis. The lysine kinases 1 and 4 (WNK1 and WNK4), identified as hyperactive in the hereditary disease pseudohypoaldosteronism typ...

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Detalles Bibliográficos
Autores principales: Gallafassi, E.A., Bezerra, M.B., Rebouças, N.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925193/
https://www.ncbi.nlm.nih.gov/pubmed/36790288
http://dx.doi.org/10.1590/1414-431X2023e12392