ATR Inhibitor Synergizes PARP Inhibitor Cytotoxicity in Homologous Recombination Repair Deficiency TK6 Cell Lines

The inhibition of poly(ADP-ribose) polymerases (PARPs) and ataxia telangiectasia and Rad3-related (ATR) would be an alternative approach for cancer treatments. The aim of this study is to investigate the synergy of the different combinations of PARP inhibitors (olaparib, talazoparib, or veliparib) a...

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Detalles Bibliográficos
Autores principales: Wikiniyadhanee, Rakkreat, Lerksuthirat, Tassanee, Stitchantrakul, Wasana, Chitphuk, Sermsiri, Takeda, Shunichi, Dejsuphong, Donniphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925244/
https://www.ncbi.nlm.nih.gov/pubmed/36794257
http://dx.doi.org/10.1155/2023/7891753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925244/
https://www.ncbi.nlm.nih.gov/pubmed/36794257
http://dx.doi.org/10.1155/2023/7891753

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