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ATR Inhibitor Synergizes PARP Inhibitor Cytotoxicity in Homologous Recombination Repair Deficiency TK6 Cell Lines
The inhibition of poly(ADP-ribose) polymerases (PARPs) and ataxia telangiectasia and Rad3-related (ATR) would be an alternative approach for cancer treatments. The aim of this study is to investigate the synergy of the different combinations of PARP inhibitors (olaparib, talazoparib, or veliparib) a...
Autores principales: | Wikiniyadhanee, Rakkreat, Lerksuthirat, Tassanee, Stitchantrakul, Wasana, Chitphuk, Sermsiri, Takeda, Shunichi, Dejsuphong, Donniphat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925244/ https://www.ncbi.nlm.nih.gov/pubmed/36794257 http://dx.doi.org/10.1155/2023/7891753 |
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