Suppression of GCH1 Sensitizes Ovarian Cancer and Breast Cancer to PARP Inhibitor

BACKGROUND: Breast and ovarian cancers are common malignancies among women, contributing to a significant disease burden, and are characterized by a high level of genomic instability, owing to the failure of homologous recombination repair (HRR). Pharmacological inhibition of poly(ADP-ribose) polyme...

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Detalles Bibliográficos
Autores principales: Wang, Siyuan, Xia, Yu, Huang, Pu, Xu, Cheng, Qian, Yiyu, Fang, Tian, Gao, Qinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925261/
https://www.ncbi.nlm.nih.gov/pubmed/36793373
http://dx.doi.org/10.1155/2023/1453739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925261/
https://www.ncbi.nlm.nih.gov/pubmed/36793373
http://dx.doi.org/10.1155/2023/1453739

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