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Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair

Rationale: Whatever the mucosa primary infected, HPV-positive cancers are traditionally associated with a favorable outcome, attributable to a high sensitivity to radiation therapy. However, the direct impact of viral E6/E7 oncoproteins on the intrinsic cellular radiosensitivity (and, globally, on h...

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Detalles Bibliográficos
Autores principales: Bruyere, Diane, Roncarati, Patrick, Lebeau, Alizee, Lerho, Thomas, Poulain, Florian, Hendrick, Elodie, Pilard, Charlotte, Reynders, Celia, Ancion, Marie, Luyckx, Margaux, Renard, Michael, Jacob, Yves, Twizere, Jean-Claude, Peiffer, Raphael, Peulen, Olivier, Delvenne, Philippe, Hubert, Pascale, McBride, Alison, Gillet, Nicolas, Masson, Murielle, Herfs, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925306/
https://www.ncbi.nlm.nih.gov/pubmed/36793865
http://dx.doi.org/10.7150/thno.78091