Phloretin decreases microglia-mediated synaptic engulfment to prevent chronic mild stress-induced depression-like behaviors in the mPFC

Background: Stress is an important risk factor to induce psychiatric disorders such as depression. Phloretin (PHL), a natural dihydrochalcone compound, has been shown to exhibit anti-inflammatory and anti-oxidative effects. However, the impact of PHL on the depression and the underlying mechanism re...

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Detalles Bibliográficos
Autores principales: Li, Chenchen, Liu, Bo, Xu, Jingyi, Jing, Bin, Guo, Lijie, Wang, Liyong, Wang, Milin, Zhang, Haochen, He, Qianqian, Yu, Xin, Zhang, Yan, Xu, Zhi-Qing David, Yang, Yutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925308/
https://www.ncbi.nlm.nih.gov/pubmed/36793870
http://dx.doi.org/10.7150/thno.76553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925308/
https://www.ncbi.nlm.nih.gov/pubmed/36793870
http://dx.doi.org/10.7150/thno.76553

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