Cargando…

Phloretin decreases microglia-mediated synaptic engulfment to prevent chronic mild stress-induced depression-like behaviors in the mPFC

Background: Stress is an important risk factor to induce psychiatric disorders such as depression. Phloretin (PHL), a natural dihydrochalcone compound, has been shown to exhibit anti-inflammatory and anti-oxidative effects. However, the impact of PHL on the depression and the underlying mechanism re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Chenchen, Liu, Bo, Xu, Jingyi, Jing, Bin, Guo, Lijie, Wang, Liyong, Wang, Milin, Zhang, Haochen, He, Qianqian, Yu, Xin, Zhang, Yan, Xu, Zhi-Qing David, Yang, Yutao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925308/ https://www.ncbi.nlm.nih.gov/pubmed/36793870 http://dx.doi.org/10.7150/thno.76553

Ejemplares similares

Dysfunction of the NAc-mPFC circuit in insomnia disorder
por: Shao, Ziqiang, et al.
Publicado: (2020)

HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain
por: Du, Yu, et al.
Publicado: (2022)

Microglia activation in the mPFC mediates anxiety‐like behaviors caused by Staphylococcus aureus strain USA300
por: Zou, Jiao, et al.
Publicado: (2022)

Amygdala GABA Neurons Project To vlPAG And mPFC
por: Sun, Ying, et al.
Publicado: (2019)

PS205. Innate immune molecules activate microglia in mPFC to induce neuronal and emotional changes in mice.
por: Kitaoka, Shiho, et al.
Publicado: (2016)

Spontaneous synchronous network activity in the neonatal development of mPFC in mice
por: Pires, Johny, et al.
Publicado: (2021)

NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway
por: Wang, Wenjiao, et al.
Publicado: (2019)

PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy
por: Benetatos, Joseph, et al.
Publicado: (2020)

Social Behavior Is Modulated by Valence-Encoding mPFC-Amygdala Sub-circuitry
por: Huang, Wen-Chin, et al.
Publicado: (2020)

The role of mPFC and MTL neurons in human choice under goal-conflict
por: Gazit, Tomer, et al.
Publicado: (2020)

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
por: Fogaça, Manoela V., et al.
Publicado: (2020)

Neural Representation in mPFC Reveals Hidden Selfish Motivation in White Lies
por: Kim, JuYoung, et al.
Publicado: (2021)

Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model
por: Li, Yuzhe, et al.
Publicado: (2016)

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
por: Klune, Cassandra B, et al.
Publicado: (2021)

Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence
por: Zhang, Yu, et al.
Publicado: (2017)

Nedd4l downregulation of NRG1 in the mPFC induces depression-like behaviour in CSDS mice
por: Xu, Jia, et al.
Publicado: (2020)

SIRT1 activation attenuates microglia-mediated synaptic engulfment in postoperative cognitive dysfunction
por: Sun, Yi, et al.
Publicado: (2022)

Activation of dopaminergic VTA inputs to the mPFC ameliorates chronic stress‐induced breast tumor progression
por: Xu, Xi‐Rong, et al.
Publicado: (2020)

Chemogenetic activation of the HPC-mPFC pathway improves cognitive dysfunction in lipopolysaccharide -induced brain injury
por: Ge, Chenglong, et al.
Publicado: (2023)

Decreased phase information transfer from the mPFC to the BLA: During exploratory behavior in CUMS rats
por: Cao, Qingying, et al.
Publicado: (2023)

Author Correction: The role of mPFC and MTL neurons in human choice under goal-conflict
por: Gazit, Tomer, et al.
Publicado: (2020)

Natural sleep loss is associated with lower mPFC activity during negative distracter processing
por: Dimitrov, Annika, et al.
Publicado: (2021)

The Neurotrophic Receptor Tyrosine Kinase in MEC-mPFC Neurons Contributes to Remote Memory Consolidation
por: Hong, Jongryul, et al.
Publicado: (2022)

Optogenetic stimulation of mPFC pyramidal neurons as a conditioned stimulus supports associative learning in rats
por: Wu, Guang-yan, et al.
Publicado: (2015)

Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence
por: Xu, Hang, et al.
Publicado: (2016)

Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep–Wake EEG Disturbances
por: Lou, Tingting, et al.
Publicado: (2020)

Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory
por: Wu, Jing, et al.
Publicado: (2023)

Decreased Phase–Amplitude Coupling Between the mPFC and BLA During Exploratory Behaviour in Chronic Unpredictable Mild Stress-Induced Depression Model of Rats
por: Wang, Zihe, et al.
Publicado: (2021)

Synergistic, long-term effects of glutamate dehydrogenase 1 deficiency and mild stress on cognitive function and mPFC gene and miRNA expression
por: Asraf, Kfir, et al.
Publicado: (2023)

Effect of Physical Activity on Symptoms of Morphine Addiction in Rats, after and before of Lesion of the mPFC Area
por: Saedi Marghmaleki, Vajiheh, et al.
Publicado: (2013)

Subregional differences in the generation of fast network oscillations in the rat medial prefrontal cortex (mPFC) in vitro
por: Glykos, Vasileios, et al.
Publicado: (2015)

Nucleus Accumbens Shell and mPFC but Not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking
por: Lei, Kelly, et al.
Publicado: (2016)

Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice
por: Kayyal, Haneen, et al.
Publicado: (2021)

Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear
por: Lee, Boyoung, et al.
Publicado: (2022)

Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques
por: Giacometti, C., et al.
Publicado: (2023)

BDNF-GSK-3β-β-Catenin Pathway in the mPFC Is Involved in Antidepressant-Like Effects of Morinda officinalis Oligosaccharides in Rats
por: Xu, Ling-Zhi, et al.
Publicado: (2016)

LIMK1/2 in the mPFC Plays a Role in Chronic Stress-Induced Depressive-Like Effects in Mice
por: Gao, Ting-Ting, et al.
Publicado: (2020)

Involvement of Oxytocin Receptor/Erk/MAPK Signaling in the mPFC in Early Life Stress-Induced Autistic-Like Behaviors
por: Wei, Jinbao, et al.
Publicado: (2020)

The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC
por: Morrison, Gladys, et al.
Publicado: (2019)

Distinctive roles of mPFC subregions in forming impressions and guiding social interaction based on others’ social behaviour
por: Lim, Gahyun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hakf3gpt5n203mldbo354okbd0