Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression

Background: Depression is a mental disorder that poses a serious threat to human health. Adult hippocampal neurogenesis (AHN) is closely associated with the efficacy of antidepressants. Chronic treatment with corticosterone (CORT), a well-validated pharmacological stressor, induces depressive-like b...

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Detalles Bibliográficos
Autores principales: Zhang, Kuo, Wang, Fan, Zhai, Mengying, He, Meiyao, Hu, Yuxuan, Feng, Lijin, Li, Yuting, Yang, Jingyu, Wu, Chunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925310/
https://www.ncbi.nlm.nih.gov/pubmed/36793868
http://dx.doi.org/10.7150/thno.81067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925310/
https://www.ncbi.nlm.nih.gov/pubmed/36793868
http://dx.doi.org/10.7150/thno.81067

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