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Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression
Background: Depression is a mental disorder that poses a serious threat to human health. Adult hippocampal neurogenesis (AHN) is closely associated with the efficacy of antidepressants. Chronic treatment with corticosterone (CORT), a well-validated pharmacological stressor, induces depressive-like b...
Autores principales: | Zhang, Kuo, Wang, Fan, Zhai, Mengying, He, Meiyao, Hu, Yuxuan, Feng, Lijin, Li, Yuting, Yang, Jingyu, Wu, Chunfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925310/ https://www.ncbi.nlm.nih.gov/pubmed/36793868 http://dx.doi.org/10.7150/thno.81067 |
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