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Using a novel rapid alternating steering angles pulse sequence to evaluate the impact of theranostic ultrasound-mediated ultra-short pulse length on blood-brain barrier opening volume and closure, cavitation mapping, drug delivery feasibility, and safety

Background: Focused ultrasound (FUS)-mediated blood-brain barrier (BBB) opening is a noninvasive, safe and reversible technique for targeted drug delivery to the brain. Most preclinical systems developed to perform and monitor BBB opening are comprised of a separate geometrically focused transducer...

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Detalles Bibliográficos
Autores principales: Batts, Alec J., Ji, Robin, Noel, Rebecca L., Kline-Schoder, Alina R., Bae, Sua, Kwon, Nancy, Konofagou, Elisa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925313/
https://www.ncbi.nlm.nih.gov/pubmed/36793858
http://dx.doi.org/10.7150/thno.76199