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EIF4A3 stabilizes the expression of lncRNA AGAP2‐AS1 to activate cancer‐associated fibroblasts via MyD88/NF‐κb signaling

BACKGROUND: Lung cancer (LC) is a fatal malignancy and often accompanied with converting normal fibroblasts to cancer‐associated fibroblasts (CAFs). Exosomal lncRNA AGAP2‐AS1 has been elucidated to be a potent prognostic factor for LC, while its role in activating CAFs is largely unknown. METHODS: W...

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Detalles Bibliográficos
Autores principales: Xu, Qingqing, Zhao, Tingting, Han, Honghao, Fan, Jiahao, Xie, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925344/
https://www.ncbi.nlm.nih.gov/pubmed/36541122
http://dx.doi.org/10.1111/1759-7714.14762