Phosphoproteomic analysis of metformin signaling in colorectal cancer cells elucidates mechanism of action and potential therapeutic opportunities

BACKGROUND: The biguanide drug metformin is a safe and widely prescribed drug for type 2 diabetes. Interestingly, hundreds of clinical trials have been set to evaluate the potential role of metformin in the prevention and treatment of cancer including colorectal cancer (CRC). However, the “metformin...

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Detalles Bibliográficos
Autores principales: Salovska, Barbora, Gao, Erli, Müller‐Dott, Sophia, Li, Wenxue, Cordon, Carlos Chacon, Wang, Shisheng, Dugourd, Aurelien, Rosenberger, George, Saez‐Rodriguez, Julio, Liu, Yansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925373/
https://www.ncbi.nlm.nih.gov/pubmed/36781298
http://dx.doi.org/10.1002/ctm2.1179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925373/
https://www.ncbi.nlm.nih.gov/pubmed/36781298
http://dx.doi.org/10.1002/ctm2.1179

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