Genome-wide RNA polymerase stalling shapes the transcriptome during aging

Gene expression profiling has identified numerous processes altered in aging, but how these changes arise is largely unknown. Here we combined nascent RNA sequencing and RNA polymerase II chromatin immunoprecipitation followed by sequencing to elucidate the underlying mechanisms triggering gene expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gyenis, Akos, Chang, Jiang, Demmers, Joris J. P. G., Bruens, Serena T., Barnhoorn, Sander, Brandt, Renata M. C., Baar, Marjolein P., Raseta, Marko, Derks, Kasper W. J., Hoeijmakers, Jan H. J., Pothof, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925383/
https://www.ncbi.nlm.nih.gov/pubmed/36658433
http://dx.doi.org/10.1038/s41588-022-01279-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925383/
https://www.ncbi.nlm.nih.gov/pubmed/36658433
http://dx.doi.org/10.1038/s41588-022-01279-6

Ejemplares similares