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Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheumatoid arthritis in mice

Massive intra-articular infiltration of proinflammatory macrophages is a prominent feature of rheumatoid arthritis (RA) lesions, which are thought to underlie articular immune dysfunction, severe synovitis and ultimately joint erosion. Here we report an efferocytosis-informed nanoimitator (EINI) for...

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Detalles Bibliográficos
Autores principales: Zhang, Shengchang, Liu, Ying, Jing, Weiqiang, Chai, Qihao, Tang, Chunwei, Li, Ziyang, Man, Zhentao, Chen, Chen, Zhang, Jing, Sun, Peng, Zhang, Rui, Yang, Zhenmei, Han, Maosen, Wang, Yan, Wei, Xia, Li, Jun, Li, Wei, Abdalla, Mohnad, Yu, Gongchang, Shi, Bin, Zhang, Yuankai, Zhao, Kun, Jiang, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925448/
https://www.ncbi.nlm.nih.gov/pubmed/36781864
http://dx.doi.org/10.1038/s41467-023-36468-2