Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change

Individuals at distinct stages of Alzheimer’s disease (AD) show abnormal electroencephalographic activity, which has been linked to network hyperexcitability and cognitive decline. However, whether pro-excitatory changes at the synaptic level are observed in brain areas affected early in AD, and if...

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Detalles Bibliográficos
Autores principales: Scaduto, Pietro, Lauterborn, Julie C., Cox, Conor D., Fracassi, Anna, Zeppillo, Tommaso, Gutierrez, Berenice A., Keene, C. Dirk, Crane, Paul K., Mukherjee, Shubhabrata, Russell, William K., Taglialatela, Giulio, Limon, Agenor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925531/
https://www.ncbi.nlm.nih.gov/pubmed/36538112
http://dx.doi.org/10.1007/s00401-022-02526-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925531/
https://www.ncbi.nlm.nih.gov/pubmed/36538112
http://dx.doi.org/10.1007/s00401-022-02526-0

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