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Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change
Individuals at distinct stages of Alzheimer’s disease (AD) show abnormal electroencephalographic activity, which has been linked to network hyperexcitability and cognitive decline. However, whether pro-excitatory changes at the synaptic level are observed in brain areas affected early in AD, and if...
Autores principales: | Scaduto, Pietro, Lauterborn, Julie C., Cox, Conor D., Fracassi, Anna, Zeppillo, Tommaso, Gutierrez, Berenice A., Keene, C. Dirk, Crane, Paul K., Mukherjee, Shubhabrata, Russell, William K., Taglialatela, Giulio, Limon, Agenor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925531/ https://www.ncbi.nlm.nih.gov/pubmed/36538112 http://dx.doi.org/10.1007/s00401-022-02526-0 |
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