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Genes that are Used Together are More Likely to be Fused Together in Evolution by Mutational Mechanisms: A Bioinformatic Test of the Used-Fused Hypothesis

Cases of parallel or recurrent gene fusions in evolution as well as in genetic disease and cancer are difficult to explain, because unlike point mutations, they can require the repetition of a similar configuration of multiple breakpoints rather than the repetition of a single point mutation. The us...

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Detalles Bibliográficos
Autores principales: Bolotin, Evgeni, Melamed, Daniel, Livnat, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925542/
https://www.ncbi.nlm.nih.gov/pubmed/36816837
http://dx.doi.org/10.1007/s11692-022-09579-9