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Effects of trastuzumab and trastuzumab emtansine on corrected QT interval and left ventricular ejection fraction in patients with metastatic (HER2+) breast cancer

BACKGROUND: Trastuzumab and trastuzumab emtansine are specific antibody and antibody–drug conjugates used in the treatment of human epidermal growth factor receptor 2 (HER2) positive metastatic breast cancer. The aim of this study was to test their effect on the QTc interval duration and left ventri...

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Detalles Bibliográficos
Autores principales: Levicki, Rea, Lovrić Benčić, Martina, Ivanac Vranešić, Irena, Bradić, Lada, Begovac, Marta, Jug, Juraj, Dedić Plavetić, Natalija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925620/
https://www.ncbi.nlm.nih.gov/pubmed/36781707
http://dx.doi.org/10.1186/s43044-023-00331-y