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Metformin increases bone marrow adipose tissue by promoting mesenchymal stromal cells apoptosis

Bone marrow adipose tissue (MAT) has the potential to exert both local and systemic effects on metabolic homeostasis. As a first-line drug used to treat type 2 diabetes mellitus, metformin has conflicting effects on MAT and bone marrow mesenchymal stem cell (BM-MSC) differentiation. Through a series...

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Detalles Bibliográficos
Autores principales: Duan, Wu, Zou, Huajie, Zang, Nan, Ma, Dongxia, Yang, Bo, Zhu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925686/
https://www.ncbi.nlm.nih.gov/pubmed/36645914
http://dx.doi.org/10.18632/aging.204486