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Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice

Alzheimer’s disease (AD) is associated with progressive neuronal degeneration as amyloid-beta (Aβ) and tau proteins accumulate in the brain. Glial cells were recently reported to play an important role in the development of AD. However, little is known about the role of oligodendrocytes in AD pathog...

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Detalles Bibliográficos
Autores principales: Park, Hanseul, Cho, Byounggook, Kim, Hongwon, Saito, Takashi, Saido, Takaomi C., Won, Kyoung-Jae, Kim, Jongpil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925742/
https://www.ncbi.nlm.nih.gov/pubmed/36781874
http://dx.doi.org/10.1038/s41467-023-36519-8