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Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice

Cataplexy is one of the symptoms of type 1 narcolepsy, characterized by a sudden loss of muscle tone. It can be seen as a behavioral index of salience, predominantly positive emotion, since it is triggered by laughter in humans and palatable foods in mice. In our previous study using chemogenetic te...

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Detalles Bibliográficos
Autores principales: Kawashima, Shigetaka, Lou, Fan, Kusumoto-Yoshida, Ikue, Hao, Liying, Kuwaki, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925750/
https://www.ncbi.nlm.nih.gov/pubmed/36781929
http://dx.doi.org/10.1038/s41598-023-29488-x