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Methylation and expression of glucocorticoid receptor exon-1 variants and FKBP5 in teenage suicide-completers

A dysregulated hypothalamic-pituitary-adrenal (HPA) axis has repeatedly been demonstrated to play a fundamental role in psychiatric disorders and suicide, yet the mechanisms underlying this dysregulation are not clear. Decreased expression of the glucocorticoid receptor (GR) gene, which is also susc...

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Detalles Bibliográficos
Autores principales: Rizavi, Hooriyah S., Khan, Omar S., Zhang, Hui, Bhaumik, Runa, Grayson, Dennis R., Pandey, Ghanshyam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925759/
https://www.ncbi.nlm.nih.gov/pubmed/36781843
http://dx.doi.org/10.1038/s41398-023-02345-1