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CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells

Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including motor neuron disorders. Motor neuron targeted upregulation of autophagy may serve as a promising therapeutic approach. Lanthionine ketenamine...

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Detalles Bibliográficos
Autores principales: Gonzalez Porras, Maria A., Gransee, Heather M., Denton, Travis T., Shen, Dunxin, Webb, Kevin L., Brinker, C. Jeffrey, Noureddine, Achraf, Sieck, Gary C., Mantilla, Carlos B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925763/
https://www.ncbi.nlm.nih.gov/pubmed/36781993
http://dx.doi.org/10.1038/s41598-023-29437-8