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CTB-targeted protocells enhance ability of lanthionine ketenamine analogs to induce autophagy in motor neuron-like cells
Impaired autophagy, a cellular digestion process that eliminates proteins and damaged organelles, has been implicated in neurodegenerative diseases, including motor neuron disorders. Motor neuron targeted upregulation of autophagy may serve as a promising therapeutic approach. Lanthionine ketenamine...
Autores principales: | Gonzalez Porras, Maria A., Gransee, Heather M., Denton, Travis T., Shen, Dunxin, Webb, Kevin L., Brinker, C. Jeffrey, Noureddine, Achraf, Sieck, Gary C., Mantilla, Carlos B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925763/ https://www.ncbi.nlm.nih.gov/pubmed/36781993 http://dx.doi.org/10.1038/s41598-023-29437-8 |
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