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Persistent homology analysis distinguishes pathological bone microstructure in non-linear microscopy images
We present a topological method for the detection and quantification of bone microstructure from non-linear microscopy images. Specifically, we analyse second harmonic generation (SHG) and two photon excited autofluorescence (TPaF) images of bone tissue which capture the distribution of matrix (fibr...
Autores principales: | Pritchard, Ysanne, Sharma, Aikta, Clarkin, Claire, Ogden, Helen, Mahajan, Sumeet, Sánchez-García, Rubén J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925777/ https://www.ncbi.nlm.nih.gov/pubmed/36781895 http://dx.doi.org/10.1038/s41598-023-28985-3 |
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