Illumination of a progressive allosteric mechanism mediating the glycine receptor activation

Pentameric ligand-gated ion channel mediate signal transduction at chemical synapses by transiting between resting and open states upon neurotransmitter binding. Here, we investigate the gating mechanism of the glycine receptor fluorescently labeled at the extracellular-transmembrane interface by vo...

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Detalles Bibliográficos
Autores principales: Shi, Sophie, Lefebvre, Solène N., Peverini, Laurie, Cerdan, Adrien H., Milán Rodríguez, Paula, Gielen, Marc, Changeux, Jean-Pierre, Cecchini, Marco, Corringer, Pierre-Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925812/
https://www.ncbi.nlm.nih.gov/pubmed/36781912
http://dx.doi.org/10.1038/s41467-023-36471-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925812/
https://www.ncbi.nlm.nih.gov/pubmed/36781912
http://dx.doi.org/10.1038/s41467-023-36471-7

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