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Long range inter-chromosomal interaction of Oct4 distal enhancer loci regulates ESCs pluripotency

Nuclear architecture underlies the transcriptional programs within the cell to establish cell identity. As previously demonstrated, long-range chromatin interactions of the Oct4 distal enhancer (DE) are correlated with active transcription in naïve state embryonic stem cells. Here, we identify and c...

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Detalles Bibliográficos
Autores principales: Moon, Byoung-San, Huang, David, Gao, Fan, Cai, Mingyang, Lyu, Guochang, Zhang, Lei, Chen, Jun, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925822/
https://www.ncbi.nlm.nih.gov/pubmed/36781845
http://dx.doi.org/10.1038/s41420-023-01363-8