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Structure and dynamics of the EGFR/HER2 heterodimer

HER2 belongs to the human epidermal growth factor receptor tyrosine kinase family. Its overexpression or hyperactivation is a leading cause for multiple types of cancers. HER2 functions mainly through dimerization with other family members, such as EGFR. However, the molecular details for heterodime...

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Detalles Bibliográficos
Autores principales: Bai, Xue, Sun, Pengyu, Wang, Xinghao, Long, Changkun, Liao, Shuyun, Dang, Song, Zhuang, Shangshang, Du, Yongtao, Zhang, Xinyi, Li, Nan, He, Kangmin, Zhang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925823/
https://www.ncbi.nlm.nih.gov/pubmed/36781849
http://dx.doi.org/10.1038/s41421-023-00523-5