Effects of combinations of gapmer antisense oligonucleotides on the target reduction

BACKGROUND: The co-administration of several therapeutic oligonucleotides targeting the same transcript is a beneficial approach. It broadens the target sites for diseases associated with various mutations or splice variants. However, little is known how a combination of antisense oligonucleotides (...

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Detalles Bibliográficos
Autores principales: Yanagidaira, Mitsugu, Yoshioka, Kotaro, Nagata, Tetsuya, Nakao, Shoichi, Miyata, Kenichi, Yokota, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925919/
https://www.ncbi.nlm.nih.gov/pubmed/36787053
http://dx.doi.org/10.1007/s11033-022-08224-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925919/
https://www.ncbi.nlm.nih.gov/pubmed/36787053
http://dx.doi.org/10.1007/s11033-022-08224-0

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