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Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants

BACKGROUND: Lysergic acid diethylamide (LSD) is currently being investigated in psychedelic-assisted therapy. LSD has a long duration of acute action of 8–11 hours. It produces its acute psychedelic effects via stimulation of the serotonin 5-hydroxytryptamine-2A (HT(2A)) receptor. Administration of...

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Detalles Bibliográficos
Autores principales: Becker, Anna M, Klaiber, Aaron, Holze, Friederike, Istampoulouoglou, Ioanna, Duthaler, Urs, Varghese, Nimmy, Eckert, Anne, Liechti, Matthias E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926053/
https://www.ncbi.nlm.nih.gov/pubmed/36342343
http://dx.doi.org/10.1093/ijnp/pyac075