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Selective Inhibition of the MK2 Pathway: Data From a Phase IIa Randomized Clinical Trial in Rheumatoid Arthritis

OBJECTIVE: The study objective was to evaluate the safety, tolerability, pharmacodynamics, and preliminary efficacy of ATI‐450 with methotrexate in patients with rheumatoid arthritis (RA). METHODS: A parallel‐assignment, placebo‐controlled, investigator‐blinded/patient‐blinded multicenter study eval...

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Detalles Bibliográficos
Autores principales: Gordon, David, Kivitz, Alan, Singhal, Atul, Burt, David, Bangs, Madison C., Huff, Emma E., Hope, Heidi Rath, Monahan, Joseph B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926068/
https://www.ncbi.nlm.nih.gov/pubmed/36604812
http://dx.doi.org/10.1002/acr2.11517