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Optimizing a therapy for opiate use disorders: Characterizing ondansetron pharmacokinetics in blood and brain
Administration of a widely used 5‐hydroxytryptamine receptor (5HT(3A)R) antagonist (ondansetron) potently inhibited the development of experimentally induced opioid dependence and withdrawal responses in mice and humans. However, in several studies examining withdrawal symptoms in subjects with chro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926069/ https://www.ncbi.nlm.nih.gov/pubmed/36305236 http://dx.doi.org/10.1111/cts.13440 |