Comparison of P‐glycoprotein function in peripheral blood mononuclear cells ex vivo in stable Black and White male and female kidney transplant recipients

Kidney allograft survival remains poorer in Black compared to White recipients due to racial differences in calcineurin inhibitor (CNI) pharmacology. P‐glycoprotein (P‐gp), an ABC efflux transporter expressed in peripheral blood mononuclear cells (PBMCs), modulates CNI pharmacokinetics and intracell...

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Detalles Bibliográficos
Autores principales: Tornatore, Kathleen M., Attwood, Kris, Brazeau, Daniel, Sprowl, Jason, Chang, Shirley, Gundroo, Aijaz, Minderman, Hans, Venuto, Rocco C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926080/
https://www.ncbi.nlm.nih.gov/pubmed/36352830
http://dx.doi.org/10.1111/cts.13444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926080/
https://www.ncbi.nlm.nih.gov/pubmed/36352830
http://dx.doi.org/10.1111/cts.13444

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