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Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration

Visible light (400–800 nm) can lead to photooxidation of protein formulations, which might impair protein integrity. However, the relevant mechanism of photooxidation upon visible light exposure is still unclear for therapeutic proteins, since proteinogenic structures do not absorb light in the visi...

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Detalles Bibliográficos
Autores principales: Hipper, Elena, Lehmann, Florian, Kaiser, Wolfgang, Hübner, Göran, Buske, Julia, Blech, Michaela, Hinderberger, Dariush, Garidel, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926095/
https://www.ncbi.nlm.nih.gov/pubmed/36798831
http://dx.doi.org/10.1016/j.ijpx.2022.100155