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Impaired immune response and barrier function in GSPD-1-deficient C. elegans infected with Klebsiella pneumoniae

gspd-1-RNAi knockdown Caenorhabditis elegans was used as an immune-compromised model to investigate the role of G6PD in host-pathogen interactions. A shorted lifespan, increased bacterial burden and bacterial translocation were observed in gspd-1-knockdown C. elegans infected with Klebsiella pneumon...

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Detalles Bibliográficos
Autores principales: Yang, Wan-Hua, Chen, Po-Hsiang, Chang, Hung-Hsin, Kwok, Hong Luen, Stern, Arnold, Soo, Po-Chi, Chen, Jiun-Han, Yang, Hung-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926097/
https://www.ncbi.nlm.nih.gov/pubmed/36798906
http://dx.doi.org/10.1016/j.crmicr.2023.100181