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Modeling congenital brain malformations with brain organoids: a narrative review

BACKGROUND AND OBJECTIVE: During embryonic development, the dysregulation of the proliferation and differentiation of neuronal progenitors triggers congenital brain malformations. These malformations are common causes of morbidity and mortality in patients younger than 2 years old. Animal models hav...

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Detalles Bibliográficos
Autores principales: Ji, Xiao-Shan, Ji, Xiao-Li, Xiong, Man, Zhou, Wen-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926131/
https://www.ncbi.nlm.nih.gov/pubmed/36798935
http://dx.doi.org/10.21037/tp-22-239