Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X

Sheet-like membrane protrusions at the leading edge, termed lamellipodia, drive 2D-cell migration using active actin polymerization. Microspikes comprise actin-filament bundles embedded within lamellipodia, but the molecular mechanisms driving their formation and their potential functional relevance...

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Detalles Bibliográficos
Autores principales: Pokrant, Thomas, Hein, Jens Ingo, Körber, Sarah, Disanza, Andrea, Pich, Andreas, Scita, Giorgio, Rottner, Klemens, Faix, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926217/
https://www.ncbi.nlm.nih.gov/pubmed/36598940
http://dx.doi.org/10.1073/pnas.2217437120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926217/
https://www.ncbi.nlm.nih.gov/pubmed/36598940
http://dx.doi.org/10.1073/pnas.2217437120

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