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Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures

Human pluripotent stem cell (hPSC)-derived retinal organoids (ROs) can efficiently and reproducibly generate retinal neurons that have potential for use in cell replacement strategies [Capowski et al., Development 146, dev171686 (2019)]. The ability of these lab-grown retinal neurons to form new syn...

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Detalles Bibliográficos
Autores principales: Ludwig, Allison L., Mayerl, Steven J., Gao, Yu, Banghart, Mark, Bacig, Cole, Fernandez Zepeda, Maria A., Zhao, Xinyu, Gamm, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926218/
https://www.ncbi.nlm.nih.gov/pubmed/36598946
http://dx.doi.org/10.1073/pnas.2213418120