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Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X syndrome

Layer 5 (L5) pyramidal neurons receive predictive and sensory inputs in a compartmentalized manner at their apical and basal dendrites, respectively. To uncover how integration of sensory inputs is affected in autism spectrum disorders (ASD), we used two-photon glutamate uncaging to activate spines...

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Detalles Bibliográficos
Autores principales: Mitchell, Diana E., Miranda-Rottmann, Soledad, Blanchard, Maxime, Araya, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926222/
https://www.ncbi.nlm.nih.gov/pubmed/36595706
http://dx.doi.org/10.1073/pnas.2208963120