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Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice

BACKGROUND: Keratitis ichthyosis deafness (KID) syndrome is a rare disorder caused by hemichannel (HC) activating gain-of-function mutations in the GJB2 gene encoding connexin (Cx) 26, for which there is no cure, or current treatments based upon the mechanism of disease causation. METHODS: We applie...

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Detalles Bibliográficos
Autores principales:	Peres, Chiara, Sellitto, Caterina, Nardin, Chiara, Putti, Sabrina, Orsini, Tiziana, Di Pietro, Chiara, Marazziti, Daniela, Vitiello, Adriana, Calistri, Arianna, Rigamonti, Mara, Scavizzi, Ferdinando, Raspa, Marcello, Zonta, Francesco, Yang, Guang, White, Thomas W., Mammano, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926223/ https://www.ncbi.nlm.nih.gov/pubmed/36736132 http://dx.doi.org/10.1016/j.ebiom.2023.104453

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