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DNA topoisomerase 2-associated proteins PATL1 and PATL2 regulate the biogenesis of hERG K(+) channels
The human ether-a-go-go-related gene (hERG) K(+) channel conducts a rapidly activating delayed rectifier K(+) current (I(Kr)), which is essential for normal electrical activity of the heart. Precise regulation of hERG channel biogenesis is critical for serving its physiological functions, and deviat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926248/ https://www.ncbi.nlm.nih.gov/pubmed/36608291 http://dx.doi.org/10.1073/pnas.2206146120 |