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Human ERG oncoprotein represses a Drosophila LIM domain binding protein–coding gene Chip

Human ETS Related Gene, ERG, a master transcription factor, turns oncogenic upon its out-of-context activation in diverse developmental lineages. However, the mechanism underlying its lineage-specific activation of Notch (N), Wnt, or EZH2—three well-characterized oncogenic targets of ERG—remains elu...

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Detalles Bibliográficos
Autores principales: Bharti, Mahima, Bajpai, Anjali, Rautela, Umanshi, Manzar, Nishat, Ateeq, Bushra, Sinha, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926275/
https://www.ncbi.nlm.nih.gov/pubmed/36595681
http://dx.doi.org/10.1073/pnas.2211189119