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Comprehensive analysis of RNA-binding protein SRSF2-dependent alternative splicing signature in malignant proliferation of colorectal carcinoma

Aberrant expression of serine/arginine-rich splicing factor 2 (SRSF2) can lead to tumorigenesis, but its molecular mechanism in colorectal cancer is currently unknown. Herein, we found SRSF2 to be highly expressed in human colorectal cancer (CRC) samples compared with normal tissues. Both in vitro a...

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Detalles Bibliográficos
Autores principales: Liu, Weizhen, Li, Dongfang, Lu, Ting, Zhang, Haosheng, Chen, Zhengxin, Ruan, Qinli, Zheng, Zihui, Chen, Linlin, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926302/
https://www.ncbi.nlm.nih.gov/pubmed/36623729
http://dx.doi.org/10.1016/j.jbc.2023.102876