Cargando…

Comprehensive analysis of RNA-binding protein SRSF2-dependent alternative splicing signature in malignant proliferation of colorectal carcinoma

Aberrant expression of serine/arginine-rich splicing factor 2 (SRSF2) can lead to tumorigenesis, but its molecular mechanism in colorectal cancer is currently unknown. Herein, we found SRSF2 to be highly expressed in human colorectal cancer (CRC) samples compared with normal tissues. Both in vitro a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Weizhen, Li, Dongfang, Lu, Ting, Zhang, Haosheng, Chen, Zhengxin, Ruan, Qinli, Zheng, Zihui, Chen, Linlin, Guo, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926302/ https://www.ncbi.nlm.nih.gov/pubmed/36623729 http://dx.doi.org/10.1016/j.jbc.2023.102876

Ejemplares similares

SRSF1-mediated alternative splicing is required for spermatogenesis
por: Lei, Wen-Long, et al.
Publicado: (2023)

SRSF3 Promotes Angiogenesis in Colorectal Cancer by Splicing SRF
por: Chen, Yinshuang, et al.
Publicado: (2022)

Oncogenic splicing factor SRSF3 regulates ILF3 alternative splicing to promote cancer cell proliferation and transformation
por: Jia, Rong, et al.
Publicado: (2019)

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium
por: Zhang, Xiaoli, et al.
Publicado: (2021)

SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing
por: Liu, Wenbo, et al.
Publicado: (2022)

Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation
por: Zhou, Xuexia, et al.
Publicado: (2014)

Relative strength of 5’ splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA
por: Choi, Namjeong, et al.
Publicado: (2021)

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage
por: Comiskey, Daniel F., et al.
Publicado: (2015)

USP15 and USP4 facilitate lung cancer cell proliferation by regulating the alternative splicing of SRSF1
por: Das, Tanuza, et al.
Publicado: (2022)

Alternative splicing of HSPA12A pre‐RNA by SRSF11 contributes to metastasis potential of colorectal cancer
por: Pan, Yao‐Jie, et al.
Publicado: (2022)

USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A(165b) alternative splicing via regulating SRSF1 and SRPK1
por: Pan, Xiu-wu, et al.
Publicado: (2021)

Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells
por: Gonçalves, Vânia, et al.
Publicado: (2014)

CircPLCE1 facilitates the malignant progression of colorectal cancer by repressing the SRSF2‐dependent PLCE1 pre‐RNA splicing
por: Chen, Zhilei, et al.
Publicado: (2021)

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
por: Hulse, Richard P., et al.
Publicado: (2016)

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements
por: Do, Dang Vinh, et al.
Publicado: (2018)

Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence
por: Shen, Ting, et al.
Publicado: (2019)

Srsf7 Establishes the Juvenile Transcriptome through Age-Dependent Alternative Splicing in Mice
por: Kadota, Yosuke, et al.
Publicado: (2020)

Srsf7 Establishes the Juvenile Transcriptome through Age-Dependent Alternative Splicing in Mice
por: Kadota, Yosuke, et al.
Publicado: (2020)

Comprehensive Analysis of Prognostic Alternative Splicing Signatures in Endometrial Cancer
por: Chen, Peigen, et al.
Publicado: (2020)

SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance
por: Sheng, Junxiu, et al.
Publicado: (2018)

Splicing factor SRSF6 mediates pleural fibrosis
por: Liang, Li-Mei, et al.
Publicado: (2021)

Genome-wide analysis of SRSF10-regulated alternative splicing by deep sequencing of chicken transcriptome
por: Zhou, Xuexia, et al.
Publicado: (2014)

SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of BAX
por: Wagner, Allison R, et al.
Publicado: (2022)

Comprehensive analysis of prognostic alternative splicing signature in cervical cancer
por: Ouyang, Dong, et al.
Publicado: (2020)

Comprehensive analysis of alternative splicing signatures in pancreatic head cancer
por: Zhou, Lingshan, et al.
Publicado: (2022)

The SRSF3-MBNL1-Acin1 circuit constitutes an emerging axis to lessen DNA fragmentation in colorectal cancer via an alternative splicing mechanism
por: Chen, Yi-Su, et al.
Publicado: (2020)

PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3
por: Chen, Dawei, et al.
Publicado: (2021)

THE SPLICING FACTOR SRSF1 REGULATES APOPTOSIS AND PROLIFERATION TO PROMOTE MAMMARY EPITHELIAL CELL TRANSFORMATION
por: Anczuków, Olga, et al.
Publicado: (2012)

Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C
por: Skrdlant, Lindsey, et al.
Publicado: (2016)

Splicing factor SRSF2-centric gene regulation
por: Li, Kun, et al.
Publicado: (2021)

Targeting Splicing Factor SRSF6 for Cancer Therapy
por: She, Wenting, et al.
Publicado: (2021)

SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma
por: Wen, Chaowei, et al.
Publicado: (2022)

CircRPAP2 regulates the alternative splicing of PTK2 by binding to SRSF1 in breast cancer
por: Yu, Yunhe, et al.
Publicado: (2022)

SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence
por: Choi, Namjeong, et al.
Publicado: (2022)

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells
por: Feng, Shenglei, et al.
Publicado: (2022)

USP39 promotes hepatocellular carcinogenesis through regulating alternative splicing in cooperation with SRSF6/HNRNPC
por: Zheng, Jingyi, et al.
Publicado: (2023)

Suppression of Selective Voltage-Gated Calcium Channels Alleviates Neuronal Degeneration and Dysfunction through Glutathione S-Transferase-Mediated Oxidative Stress Resistance in a Caenorhabditis elegans Model of Alzheimer's Disease
por: Zheng, Zihui, et al.
Publicado: (2022)

Splicing Factor SRSF1 Is Essential for Satellite Cell Proliferation and Postnatal Maturation of Neuromuscular Junctions in Mice
por: Liu, Yuguo, et al.
Publicado: (2020)

Bioinformatics analysis of SRSF1-controlled gene networks in colorectal cancer
por: Sheng, Junxiu, et al.
Publicado: (2017)

SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells
por: Liang, Yang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3c70m4ehjqtpq213bmid1htqm4